An update on bone infection and its management
8th July 2026, 19:00 to 20:00 BST
Overview
This webinar will present preclinical research performed at the AO Research Institute Davos addressing clinically driven challenges in fracture‑related infection. The webinar will cover innovations in prevention, treatment, and diagnosis. The session will first outline the development of an antibiotic‑loaded hydrogel designed to enhance local prophylaxis in the immediate post‑trauma environment. This will be followed by recent advances in bacteriophage‑based therapeutic strategies targeting established orthopaedic infections. Finally, emerging data on immunological biomarker signatures supporting the diagnosis of infected fracture non-union will be discussed.
Aims
Aim 1 — Prevention: To present preclinical development of an antibiotic‑loaded hydrogel designed to enhance local prophylaxis against fracture‑related infection in the immediate post‑trauma environment.
Aim 2 — Treatment: To discuss therapeutic strategies using bacteriophage‑based approaches for managing established orthopaedic infections, including insights from mechanistic in vitro and in vivo models.
Aim 3 — Diagnosis: To introduce emerging immunological biomarker signatures that support the diagnosis of septic nonunion, illustrating how immune profiling can inform future translational diagnostic tools.
Learning Objectives
By the end of this webinar, attendees should be able to:
- Explain how antibiotic‑loaded hydrogels can be applied as a local prophylactic strategy to prevent fracture‑related infection.
- Describe the preclinical evidence supporting the use of bacteriophage‑based approaches for treating established orthopaedic infections.
- Recognise key immunological biomarker signatures relevant to the diagnosis of septic nonunion.
Panellists
Our panellists include:
Fintan Moriarty PhD - Fintan Moriarty is a PhD scientist leading the Infection Biology Focus Area at the AO Research Institute Davos. His research centres on fracture-related infection, with particular emphasis on advanced preclinical animal models that recapitulate clinically relevant aspects of FRI, as well as the development of novel preventive and therapeutic strategies.
Sean Kelly - Retired Orthopaedic NHS practice last year. Previous Chair SSB ORTHO RCSEd. Currently undertaking NGO work in Central Africa. Generalist with special interest in Revision TKR.
CPD
1 Hour
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Recording
A recording of the webinar will be made available on this page in the days following the live broadcast.
