Science, clinical applications and outlook

23^rd November 2026, 19:00 to 20:00 GMT

Overview

This webinar explores the rapidly evolving role of stem cells and gene therapy in orthopaedics. It will examine how regenerative and genetic approaches are being used to treat musculoskeletal injuries and degenerative disorders, alongside a review of current evidence and clinical outcomes. Key challenges, safety considerations, and regulatory aspects will be discussed, as well as future directions shaping the field. Designed for orthopaedic professionals, this session provides practical insights into emerging biologic therapies and their potential to transform patient care.

Aims

This webinar aims to provide a comprehensive overview of the current state and future potential of cell-based (including stem cells and hip aspirates) and gene therapy approaches in orthopaedics. It will bridge fundamental science with clinical translation, highlighting how emerging biologic and genetic technologies are shaping the management of musculoskeletal injuries and degenerative conditions. The session will also critically appraise clinical evidence, regulatory considerations, and translational challenges to inform evidence-based practice and future research directions.

Learning Objectives

By the end of this webinar, attendees should be able to:

• Describe the biological principles underlying cell-based therapies and gene therapy approaches relevant to musculoskeletal tissue repair and regeneration.
• Differentiate between key stem cell sources and gene delivery strategies, including their mechanisms of action, advantages, and limitations in orthopaedic applications.
• Evaluate current clinical applications and evidence, including indications in trauma, cartilage repair, bone regeneration, and degenerative musculoskeletal conditions.
• Identify current challenges and translational barriers, such as scalability, standardisation, and clinical trial design.

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Panellists

Our panellists include:

Martin J. Stoddart, PhD, FRSB, FIOR

Vice-Director, AO Research Institute Davos, Program Leader – Regenerative Orthopaedics, Principal Scientist

Prof. Martin Stoddart is Vice Director of the AO Research Institute Davos and Program Leader of Regenerative Orthopaedics, specializing in progenitor cell biology and mechanoregulation for musculoskeletal tissue repair. His research focuses on mesenchymal stem cell–based therapies and how mechanical cues influence cell fate, aiming to advance regenerative treatments and rehabilitation strategies.

 

Elena Della Bella, PhD

Senior Scientist and Deputy Focus Area Leader Progenitor Cell Biology

Dr Elena Della Bella is Senior Scientist in Progenitor Cell Biology at the AO Research Institute Davos, specializing in bone regeneration, mesenchymal stem cells, and the role of non‑coding RNA in musculoskeletal repair.

CPD

1 Hour

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Recording

A recording of the webinar will be made available on this page in the days following the live broadcast.

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